Natural and artificial flavor. 13 g protein; 350 calories; 26 vitamins & minerals. Gluten-free. 50% more calories than the original. Ensure plus - 350 calories per 8 fl oz. Ensure Original - 220 calories per 8 fl oz. Contains 82.5 mg choline per serving, which is 15 % of the daily value for choline (550 mg). No. 1 recommended brand. Complete, balanced nutrition - to help maintain a healthy weight. Ensure.com. Call 1-800-986-8727; or visit Ensure.com for more information. Ensure Plus nutrition shakes are clinically proven to help gain weight. Each shake contains 16 grams of high-quality protein, 350 calories, 27 vitamins and minerals, and nutrients to support immune-system health, including vitamins A and D, zinc, and antioxidants.* Ensure Plus protein shakes provide complete, balanced nutrition and are a great meal replacement option! * Vitamins C and E. † Ensure Plus = 16 g protein per 8 fl oz vs Ensure Original = 9 g protein per 8 fl oz.